• Fri. Sep 23rd, 2022

New sample preparation system improves proteomics research productivity

ByRandall B. Phelps

Jun 6, 2022

MINNEAPOLIS–(BUSINESS WIRE)–ASMS 2022 – Thermo Fisher Scientific Inc., the global leader in serving science, helps proteomics researchers increase productivity and free up time for higher-value activities when generating high-quality samples for analysis, using a new automated sample preparation system that integrates into any LC-MS workflow.

The Thermo Scientific AccelerOme Automated Sample Preparation Platform eliminates the need for labor-intensive manual sample preparation for LC-MS analysis, including associated method development and reagent sourcing. This allows users to focus on higher value tasks. Automated sample preparation also overcomes the challenge of maintaining reproducibility with manual methodologies, and the new platform’s predefined validated methods and kit-format reagents further reduce any risk of user error. The resulting peptide samples are of consistently high quality. A new built-in UV measurement of final peptide concentration prior to LC-MS analysis enables standardization of sample peptide input for LC-MS analysis, another metric that adds to the quality, reliability and the robustness of the final experimental result. The platform supports the use of peptide standards to monitor LC-MS system performance, enabling monitoring of instrument status during acquisition or via post-acquisition data analysis.

Thermo Fisher Scientific Introduces the AccelerOme Automated Sample Preparation Platform in the 70e American Society for Mass Spectrometry (ASMS) Conference on Mass Spectrometry and Related Topics, to be held June 5-9, 2022 at Booth 400 at the Minneapolis Convention Center, Minneapolis, Minnesota and the Hilton Minneapolis Grand Ballrooms E, F, G.

“Proteomics researchers in academia and biopharmaceuticals face a range of challenges, particularly demands for speed and productivity,” said Andreas Huhmer, senior marketing manager, omics research, life sciences mass spectrometry. life, Thermo Fisher Scientific. “The appropriate automated sample preparation systems for LC-MS play a crucial role. They provide support for platforms, where flexibility and reproducibility are essential. In research labs, sample preparation systems are needed to help automate complex samples and large sample sets to quickly generate rigorous data for publication, and in biopharma, these systems deliver speed and productivity. in marketing. The AccelerOme platform provides a solution for LC-MS proteomics workflows. »

The AccelerOme sample preparation platform, designed with a unique experimental design tool, combines reliable and reproducible hardware with easy-to-use software and commercially available reagent kits for label-free multiplexing and TMT applications . A software wizard guides users through each step, making proteomics research easier for newcomers to the field. The new platform is optimized to integrate with the Thermo Scientific Orbitrap MS ecosystem. End-to-end software, sample information, and study factors are transferred from sample input through LC-MS acquisition via data analysis with Thermo Scientific Proteome Discoverer software.

For more information on Thermo Fisher solutions on display at ASMS 2022, please visit www.thermofisher.com/ASMS.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual sales of approximately $40 billion. Our mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life science research, solving complex analytical challenges, increasing their laboratory productivity, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are there to support them. Our global team delivers an unparalleled combination of innovative technology, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. For more information, please visit www.thermofisher.com.